Scientific Articles

Date	Title	Author
Aug 2004	Persistence of Mycobacterium paratuberculosis during Manufacture and Ripening of Cheddar Cheese	Donaghy JA, NL Totton, MT Rowe
July 2004	Emerging pathogens: is Mycobacterium Avium subspecies paratuberculosis zoonotic?	Greenstein R, Collins MT
2004	Crohn's disease, mycobacteria and NOD2	Behr, Semret, Poon, Schurr
Nov 2003	CROHN'S: AN INFECTIOUS DISEASE?	Karpa KD
Oct 2003	Epidemiologic and clinical characteristics of children with newly diagnosed inflammatory bowel disease in Wisconsin: a statewide population-based study	Kugathasan, et al
Jul 2003	Detection and Verification of Mycobacterium avium subsp. paratuberculosis in Fresh Ileocolonic Mucosal Biopsy Specimens from Individuals with and without Crohn's Disease	Tim J. Bull, et al
Jul 2003	Comparative evaluation of the MGIT and BACTEC culture systems for the recovery of Mycobacterium avium subsp. paratuberculosis from milk	Grant IR, et al
2003	Is Crohn's disease caused by a mycobacterium? Comparisons with leprosy, tuberculosis and Johne's disease	RJ Greenstein
Sep 2002	Seroreactivities against Saccharomyces cerevisiae and Mycobacterium avium subsp. paratuberculosis p35 and p36 antigens in Crohn's disease patients	Shafran I, et al
Aug 2002	Positive IS900 In Situ Hybridization Signals as Evidence for Role of Mycobacterium avium subsp. paratuberculosis in Etiology of Crohn's Disease	Paul J. M. Roholl, et al
Aug 2002	The role of the gut flora in health and disease, and its modification as therapy	Hart AL, et al
Jul 2002	Pasteurization of milk and the heat resistance of Mycobacterium avium subsp. paratuberculosis: a critical review of the data	Lund BM, et al
Jun 2002	Detection of Mycobacterium avium subspecies paratuberculosis specific IS900 insertion sequences in bulk-tank milk samples obtained from different regions throughout Switzerland	Corti S, et al
May 2002	Treatment of Severe CD Using Antimycobacterial Triple Therapy - Approaching a Cure?	Borody, et al
May 2002	Incidence of Mycobacterium paratuberculosis in Bulk Raw and Commercially Pasteurized Cows' Milk from Approved Dairy Processing Establishments in the United Kingdom	Irene R. Grant, et al
Apr 2002	Heat resistance of Mycobacterium avium ssp. paratuberculosis in raw milk tested in a pilot plant pasteurizer	P. Hammer, et al
Apr 2002	Intracellular vs extracellular recognition of pathogens--common concepts in mammals and flies	Girardin SE, et al
Feb 2002	Incidence of MAP in Bulk-Tank Milk Samples from Different Regions of Switzerland	Stephan, Bohler, et al
Feb 2002	Effect of Commercial-Scale High-Temperature, Short-Time Pasteurization on the Viability of Mycobacterium paratuberculosis in Naturally Infected Cows' Milk	Irene R. Grant, et al
Feb 2002	Nods: a family of cytosolic proteins that regulate the host response to pathogens	Inohara N, et al
Feb 2002	In situ identification of mycobacteria in Crohn's disease patient tissue using confocal scanning laser microscopy	Naser SA, et al
Jan 2002	Open clinical trial of rifabutin and clarithromycin therapy in Crohn's disease	Shafran I, et al
Jan 2002	Crohn's disease	Shanahan F
Jan 2002	Crohn's disease caused by Mycobacterium avium subspecies paratuberculosis: a public health tragedy whose resolution is long overdue	Hermon-Taylor J, et al
Jan 2002	Treatment of severe Crohn's disease using antimycobacterial triple therapy--approaching a cure?	Naser SA, et al
Jan 2002	Open clinical trial of rifabutin and clarithromycin therapy in Crohn's disease	Shafran I, et al
Jan 2002	Treatment with Drugs Active Against MAP Can Heal CD: More Evidence for a Neglected Public Health Tragedy	Hermon-Taylor J
2002	Survival of Mycobacterium avium ssp. paratuberculosis at high temperature short time pasteurization in a pilot plant pasteurizer at elevated temperatures and extended holding time	Hammer P, et al
Dec 2001	Identification of Mycobacterium avium subsp. paratuberculosis in biopsy specimens from patients with Crohn's disease identified by in situ hybridization	Sechi LA, et al
Dec 2001	Randomized controlled trial of clarithromycin and ethambutol in the treatment of Crohn's disease	Goodgame RW, et al
Dec 2001	ANTAGONIST: Mycobacterium avium subspecies paratuberculosis is a cause of Crohn's disease	Quirke P
Dec 2001	PROTAGONIST: Mycobacterium avium subspecies paratuberculosis is a cause of Crohn's Disease	Hermon-Taylor J
Oct 2001	The NOD: a signaling module that regulates apoptosis and host defense against pathogens.	Inohara N, et al
Jun 2001	Etiology of Crohn's disease: the role of Mycobacterium avium paratuberculosis	El-Zaatari FA, et al
May 2001	Detection of Mycobacterium avium subspecies paratuberculosis in Crohn's diseased tissues by in situ hybridization	Hulten K, et al
May 2001	A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease	Ogura Y, et al
May 2001	Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease.	Hugot JP, et al
Mar 2001	Review article: Mycobacterium avium subsp. paratuberculosis as one cause of Crohn's disease	Chamberlin W, et al
Feb 2001	Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB.	Ogura Y, et al
Feb 2001	Elevated antibody responses in patients with Crohn's disease against a 14-kDa secreted protein purified from Mycobacterium avium subsp. paratuberculosis	Olsen I, et al
Feb 2001	Mycobacterium avium ssp. paratuberculosis: its incidence, heat resistance and detection in milk and dairy products	Irene R Grant, et al
Jan 2001	Human Nod1 confers responsiveness to bacterial lipopolysaccharides	Inohara N, et al
Jan 2001	Erythema nodosum in children: a prospective study	Kakourou T, et al
2001	Isolation of Mycobacterium paratuberculosis from thin market cows at slaughter	Rossiter, C.A., Henning, W.R.
Dec 2000	Results of Multiple Diagnostic Tests for Mycobacterium avium subsp. paratuberculosis in Patients with Inflammatory Bowel Disease and in Controls	Michael T. Collins, et al
Dec 2000	In situ hybridization method for studies of cell wall deficient M. paratuberculosis in tissue samples	Hulten K, et al
Dec 2000	Pathogenesis and therapeutic aspects of Crohn's disease	Selby W
Dec 2000	Specific seroreactivity of Crohn's disease patients against p35 and p36 antigens of M. avium subsp. paratuberculosis	Naser SA, et al
Oct 2000	Association of Mycobacterium paratuberculosis in Crohn's disease and Johne's disease: A possible zoonotic threat	Tapas Kumar Goswami, et al
Oct 2000	Antibiotics as primary therapy for Crohn's disease	Chamberlin W, et al
Oct 2000	Mycobacterium avium subspecies paratuberculosis in the causation of Crohn's disease	Hermon-Taylor J
Oct 2000	Identification of cell wall deficient forms of M. avium subsp. paratuberculosis in paraffin embedded tissues from animals with Johne's disease by in situ hybridization	Hulten K, et al
Sep 2000	Molecular Epidemiology of Mycobacterium avium subsp. paratuberculosis: IS900 Restriction Fragment Length Polymorphism and IS1311 Polymorphism Analyses of Isolates from Animals and a Human in Australia	R. J. Whittington, et al
Jul 2000	Binding of bovine growth hormone to Mycobacterium avium ss paratuberculosis	Feola RP, et al
Jun 2000	Causation of Crohn's disease by Mycobacterium avium subspecies paratuberculosis	Hermon-Taylor J, et al
Jun 2000	Use of short-term culture for identification of Mycobacterium avium subsp. paratuberculosis in tissue from Crohn's disease patients	Schwartz D, et al
Apr 2000	Isolation of MAP from breast milk of Crohn's disease patients	Naser SA, et al
Mar 2000	A meta-analysis of antimycobacterial therapy for Crohn's disease	Borgaonkar M, et al
Mar 2000	Antibacterial therapy for Crohn's disease: a review emphasizing therapy directed against mycobacteria	Hulten K, et al
2000	A Causal Role for Mycobacterium avium subspecies paratuberculosis in Crohn's disease?	Cook, L.S.
2000	Identification of Mycobacterium avium ss. paratuberculosis in Crohn's tissue	Shafran, Piromalli, Schwartz, Romero Naser
2000	Heat resistance of MAP in milk	Rowe, M.T., I.R. Grant, L. Dundee, and H.J. Ball
2000	Rifabutin and Macrolide Antibiotic Treatment in Crohn's patients identified seriologically positive for MAP	Shafran, Piromalli, Naser
Dec 1999	Identification of a novel mycobacterial histone H1 homologue (HupB) as an antigenic target of pANCA monoclonal antibody and serum immunoglobulin A from patients with Crohn's disease	Cohavy O, et al
Aug 1999	Characterization of Mycobacterium paratuberculosis p36 antigen and its seroreactivities in Crohn's disease	El-Zaatari FA, et al
Jun 1999	Serum antibodies to Mycobacterium paratuberculosis in patients with Crohn's disease	Suenaga K, et al
Apr 1999	Antigen-specific B-cell unresponsiveness induced by chronic Mycobacterium avium subsp. paratuberculosis infection of cattle	Waters WR, et al
Mar 1999	Mycobacterium avium subsp. paratuberculosis in Crohn's Disease Is Serologically Positive	Saleh Naser, et al
1999	Rapid culturing and PCR detection of MAP from Crohn's disease tissue	Naser, Fenster, Romero, Schwartz, Campbell, Piromalli, Shafran.
1999	Crohn's disease: The case for bacteria	Prantera, Scribano
1999	Humoral immune response of Crohn's patients for MAP	Shafran, Fenster, Priomalli, Romero, Schwartz, Campbell, ElZataari, Naser
Dec 1998	The Causation of Crohn's Disease and Treatment with Antimicrobial Drugs	John Hermon-Taylor
Sep 1998	Isolation of Mycobacterium paratuberculosis from Milk by Immunomagnetic Separation	Grant, Ball, Rowe
Sep 1998	Human exposure to Mycobacterium paratuberculosis via pasteurised milk: a modelling approach	Nauta MJ, et al
Jul 1998	Does Mycobacterium paratuberculosis Survive Current Pasteurization Conditions?	Irene R. Grant
Jul 1998	Extraintestinal disease may be associated with Crohn's disease	Joanna Barnes, et al
Jun 1998	Crohn's disease in Olmsted County, Minnesota, 1940-1993: incidence, prevalence, and survival	Loftus EV Jr, et al
Mar 1998	Thermal Tolerance of Mycobacterium paratuberculosis	Nackmoon Sung, et al
Feb 1998	Grand Round: Mycobacterium paratuberculosis cervical lymphadenitis, followed five years later by terminal ileitis similar to Crohn's disease	John Hermon-Taylor, et al
1998	Effect of high-temperature, short time (HTST) pasteurization on milk containing low numbers of Mycobacterium paratuberculosis	Grant, Ball, Rowe
1998	Detection of Mycobacterium paratuberculosis in stool samples of patients with IBD by IS900-based PCR and colorimetric detection of amplified DNA	Del Prete, Quaranta, Lippolis, Giannuzzi, Mosca, Jirillo, Miragliotta
Dec 1997	Heat inactivation of Mycobacterium paratuberculosis in raw milk: are current pasteurization conditions effective?	Judith R. Stabel, et al
Aug 1997	Long-term sequelae to foodborne disease	McDowell RM, et al
Jun 1997	Comparative study of Mycobacterium paratuberculosis strains isolated from Crohn's disease and Johne's disease using restriction fragment length polymorphism and arbitrarily primed polymerase chain reaction	Francois B, et al
Apr 1997	Mycobacterium paratuberculosis in the intestine of patients with Crohn's disease	Gan H, et al
1997	Two-year-outcomes analysis of Crohn's disease treated with rifabutin and macrolide antibiotics	GP Gui, et al
1997	Mycobacterium paratuberculosis: a potential food-borne pathogen?	M. T. Collins
Sep 1996	On the Etiology of Crohn Disease	D Mishina, et al
Sep 1996	IS900 PCR to detect Mycobacterium paratuberculosis in retail supplies of whole pasteurized cows' milk in England and Wales	D Millar, et al
Sep 1996	Pasteurization of Mycobacterium paratuberculosis in whole milk	Chiodini R. J, et al
Feb 1996	Clarithromycin against Mycobacterium avium complex infections	Heifets LB
Feb 1996	Inactivation of Mycobacterium paratuberculosis in Cow's Milk at Pasteurization Temperatures	Grant, Ball, Neill, Rowe
1996	Survival of Mycobacterium paratuberculosis and preservation of immunoglobulin G in bovine colostrums under experimental conditions simulating pasteurization	Meylan, Rings, Shulaw, Kowalski, Bech-Nielsen, Hoffsis
Oct 1995	Johne's Disease -- The International Perspective	Michael T. Collins, et al
Sep 1995	Effect of intestinal resection on serum antibodies to the mycobacterial 45/48 kilodalton doublet antigen in Crohn's disease	Kreuzpaintner G, et al
1995	A meta-analysis of antimycobacterial therapy for Crohn's disease	Borgaonkar, MacIntosh, Fardy
Dec 1994	Effects of clarithromycin and rifabutin alone and in combination on intracellular and extracellular replication of Mycobacterium avium	N Mor, et al
Oct 1994	Mycobacterium paratuberculosis in intestinal tissue from patients with Crohn's disease demonstrated by a nested primer polymerase chain reaction	Lisby G, et al
Apr 1994	Antimycobacterial therapy in Crohn's disease: results of a controlled, double-blind trial with a multiple antibiotic regimen	Prantera C, et al
Mar 1994	Occurrence, in Crohn's disease, of antibodies directed against a species-specific recombinant polypeptide of Mycobacterium paratuberculosis	Vannuffel P, et al
Feb 1994	Detection of Mycobacterium paratuberculosis by polymerase chain reaction in children with Crohn's disease	Dell'Isola B, et al
Jan 1994	Mycobacteria and the aetiology of Crohn's diseas	Hermon-Taylor J, et al
1994	Specific detection of Mycobacterium paratuberculosis DNA associated with granulomatous tissue in Crohn's disease	Fidler, Thurrell, Johnson, Rook, McFadden
Oct 93	The Thermal Resistance of Mycobacterium paratuberculosis in raw milk under conditions simulation pasteurization	Chiodini RJ; Hermon-Taylor, J
May 1993	Identification of spheroplast-like agents isolated from tissues of patients with Crohn's disease and control tissues by polymerase chain reaction	Wall S, et al
Mar 1993	Serologic reactivity against Mycobacterium paratuberculosis antigens in patients with sarcoidosis	Reid JD, et al
Dec 1992	Mycobacteria in Crohn's disease: DNA probes identify the wood pigeon strain of Mycobacterium avium and Mycobacterium paratuberculosis from human tissue	McFadden J, et al
Dec 1992	Activity of clarithromycin compared with those of other drugs against Mycobacterium paratuberculosis and further enhancement of its extracellular and intracellular activities by ethambutol	Rastogi N, et al
1992	Historical overview and current approaches in determining a mycobacterial etiology of Crohn's disease	Chiodini RJ
1992	Polymerase chain reaction detection of Mycobacterium paratuberculosis and Mycobacterium avium subsp. silvaticum in long term cultures from Crohn's disease and control tissues	Moss, Sanderson, Tizard. Hermon-Taylor
1992	Mycobacterium paratuberculosis DNA in Crohn's disease tissue	Sanderson, Moss, Tizard, Hermon-Taylor
1992	Mycobacterium paratuberculosis cultured from milk and supramammary lymph nodes of infected asymptomatic cows	Sweeney, Whitlock, Rosenberger
Jul 1991	A new hypothesis for the aetiology of Crohn's disease--evidence from lipid metabolism and intestinal tuberculosis	Roediger WE
Apr 1991	Experimental disease in young chickens induced by a Mycobacterium paratuberculosis isolate from a patient with Crohn's disease	Van Kruiningen HJ, et al
Feb 1991	Induction of suppressor cells by Mycobacterium paratuberculosis antigen in inflammatory bowel disease	Ebert EC, et al
Feb 1991	Observations on the Kveim reaction using an animal model of granulomatous bowel disease	Mitchell IC, et al
Jan 1991	Mycobacteria and subgroups of patients in Crohn's disease	Prantera C, et al
Mar 1990	Molecular biology of Crohn's disease mycobacteria	Hermon-Taylor J, et al
1990	Experimental disease in young chickens induced by a Mycobacterium paratuberculosis isolate from a patient with Crohn's disease	Van Kruningen, Ruiz. Gumprecht
Aug 1989	Quadruple antimycobacterial chemotherapy in Crohn's disease: results at 9 months of a pilot study in 20 patients	Hampson SJ, et al
Jun 1989	Preliminary report on isolation of mycobacteria from patients with Crohn's disease	Gitnick G, et al
Feb 1989	Raised serum IgG and IgA antibodies to mycobacterial antigens in rheumatoid arthritis	Tsoulfa G, et al
Jan 1989	Crohn's disease and the mycobacterioses: a review and comparison of two disease entities	Chiodini RJ
1989	Crohn's disease and mycobacteria: two cases of Crohn's disease with high anti-mycobacterial antibody levels cured by dapsone therapy	Prantera C, et al
1989	Human gut wall reactivity to monoclonal antibodies against M. avium glycolipid in relation to Crohn's disease (preliminary results)	Blaauwgeers JL, et al
Aug 1988	Progress in culture and subculture of spheroplasts and fastidious acid-fast bacilli isolated from intestinal tissues	Markesich DC, et al
May 1987	Terminal ileitis associated with Mycobacterium avium-intracellulare infection in a homosexual man with acquired immune deficiency syndrome	Schneebaum CW, et al
May 1987	Crohn's disease-isolated mycobacteria are identical to Mycobacterium paratuberculosis, as determined by DNA probes that distinguish between mycobacterial species	McFadden JJ, et al
Jan 1987	Determination of genome size and DNA homology between an unclassified Mycobacterium species isolated from patients with Crohn's disease and other mycobacteria	McFadden JJ, et al
Jan 1987	Investigation of association of mycobacteria with inflammatory bowel disease by nucleic acid hybridization	Yoshimura HH, et al
Dec 1986	Experimental disease in infant goats induced by a Mycobacterium isolated from a patient with Crohn's disease	Van Kruiningen HJ, et al
1985	Design and interpretation of a slaughter survey of Wisconsin cull cows to estimate the prevalence of Mycobacterium paratuberculosis infection	Frisby, HR; DT Berman
1985	Experimental disease in infant goats induced by a Mycobacterium isolated from a patient with Crohn's disease.	Van Kruningen, Chiodini, Thayer, Coutu, Merkal, Runnels
Dec 1984	Possible role of mycobacteria in inflammatory bowel disease. II. Mycobacterial antibodies in Crohn's disease	Thayer WR Jr, et al
Dec 1984	Possible role of mycobacteria in inflammatory bowel disease. I. An unclassified Mycobacterium species isolated from patients with Crohn's disease	Chiodini RJ, et al
Dec 1984	In vitro antimicrobial susceptibility of a Mycobacterium sp. isolated from patients with Crohn's disease	Chiodini RJ, et al
Nov 1984	Characteristics of an unclassified Mycobacterium species isolated from patients with Crohn's disease	Chiodini RJ, et al
1984	Ruminant Paratuberculosis (Johne's disease) - The Current Status and Future Prospects	Chiodini, Van Kruiningen, Merkal
Sep 1980	Enzyme-linked immunosorbent assay (ELISA): a study of antibodies to Mycobacterium tuberculosis in the IgG, IgA and IgM classes in tuberculosis, sarcoidosis and Crohn's disease	Grange JM, et al
Sep 1978	Mycobacteria as a possible cause of inflammatory bowel disease	Burnham WR, et al
Oct 1976	Transmissible agents from human sarcoid and Crohn's disease tissues	Mitchell DN, et al

Source: http://www.crohns.org/articles/index.htm Contact PARA: http://www.crohns.org/contact.htm
Paratuberculosis Awareness & Research Association, 1999-2003.