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ABSTRACT

Antimicrob Agents Chemother 1984 Dec;26(6):930-2

In vitro antimicrobial susceptibility of a Mycobacterium sp. isolated from patients with Crohn's disease

Chiodini RJ, Van Kruiningen HJ, Thayer WR, Coutu JA, Merkal RS

The in vitro susceptibility of three strains of an unclassified Mycobacterium sp., isolated from three patients with Crohn's disease, to 23 antimicrobial agents was determined by a modified broth dilution method with 7H9 broth containing oleic acid-albumin-dextrose-catalase, Tween 80, and mycobactin J. All three strains were susceptible to streptomycin, viomycin, rifampin, clofazimine, cefazolin, amikacin, and kanamycin and resistant to p-aminosalicylic acid, cycloserine, 2-thiophenecarboxylic acid hydrazide, trimethoprim, diaminodiphenylsulfone, sulfamethoxazole, sulfadimethoxine, polymyxin B, metronidazole, neomycin, and carbenicillin. Variable results between strains were encountered with ethambutol, ethionamide, capreomycin, amoxicillin, and cephalothin.


PARA's SUMMARY

MAP ISOLATED FROM CD INTESTINAL TISSUE IS SUSCEPTIBLE TO KNOWN ANTIBIOTICS.


Source: http://www.crohns.org/articles/1984_12_930-2_aac.htm   Contact PARA: http://www.crohns.org/contact.htm
Paratuberculosis Awareness & Research Association